Limiting the Proliferation of Polyploid Cells

نویسندگان

  • Neil J. Ganem
  • David Pellman
چکیده

Many errors in cell division lead to failure of cytokinesis and the generation of tetraploid cells. Given that tetraploidy can have deleterious consequences, such as genetic instability, we discuss the mechanisms that may have evolved to directly or indirectly prevent the proliferation of these cells.

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عنوان ژورنال:
  • Cell

دوره 131  شماره 

صفحات  -

تاریخ انتشار 2007